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Brain pathology

The brain pathology theme links basic, translational and clinical research in neurological conditions.

Salford Royal is home to the internationally renowned Manchester Brain Bank, established in 1986 by Professor David Mann, and which has underpinned much of the basic and clinical research into the spectrum of frontotemporal dementia that Manchester has pioneered over 30 years.

We also contribute to a number of national and international consortia and contribute to World Health Organisation (WHO) Central Nervous System and  Endocrine Tumours Classification, as well as Royal College of Pathology Guidelines.

Our ambitions are to:

  • Introduce state-of-art quantitative approaches to tissue analysis
  • Develop research in peripheral biomarkers based on liquid biopsy
  • Develop a full understanding of inflammatory mechanisms in brain tumours, and apply this knowledge to other conditions.
  • Discover peripheral biomarkers of progression and treatment response in brain tumour patients that can be rapidly translated into clinic

Research theme lead: Professor Federico Roncaroli