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Cambridge collaboration focuses on traumatic brain injury

Colleagues at Salford recruited four participants in the first month to the TOP TBI study, a pragmatic randomised trial looking at the timing of venous thromboembolism prophylaxis for adult patients with traumatic brain injury. Professor Dan Horner is a co-investigator for the study, which is funded by the NIHR Health Technology Assessment Programme and sponsored by Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge.

Prof Horner and NCA consultant neurosurgeon Catherine McMahon have also co-authored with one of the TOP TBI chief investigators a practice review on head injury in older people taking anticoagulants. This has been published in the BMJ.

Miss McMahon is also the chief investigator for Restart tICrH, a randomised trial of timing to restart direct oral anticoagulants after traumatic intracranial haemorrhage. The NIHR-funded study will inform new guidelines in neurosurgery practice for this common problem – head injury in older people falling from a standing height affects around 25,000 people a year in the UK.

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