This study investigates whether low mood in people with psoriasis is associated with signs of inflammation in the brain. One in four individuals with psoriasis may experience low mood, which could significantly affect the course of psoriasis and their quality of life. Increased understanding of the relationship between psoriasis and low mood could help develop more targeted prevention and treatment strategies for those patients.
Who can take part?
You can take part if you are 18-60 years old, are diagnosed with psoriasis and experience low mood or depression, but have not been taking antidepressants in the last six weeks. You must be based within a 40-mile radius of Manchester (including Greater Manchester, Liverpool, Leeds, Sheffield, and Preston).
What will the research involve?
You will be required to attend two sessions:
- A screening session involving an interview
- A scanning session involving two brain scans: an MRI scan (Magnetic Resonance Imaging) & a PET scan (Positron Emission Tomography)
Time and expenses will be reimbursed.
Where will the research take place?
The research will take place at Salford Royal NHS Foundation Trust and the Wolfson Molecular Imaging Centre, University of Manchester.
Ethics approved references for this study are listed below
- Research Ethics Committee ref 19/WM/0746
For more information, please contact the study team
Email Dr Georgia Lada or call 0161 275 0000