Dr Rachel Middleton

Dr Rachel Middleton

Contact details:



 MB ChB:  University of Leeds, 1994

MRCP: Royal College of Physicians of Edinburgh, 1997

FRCP: Royal College of Physicians of London, 2009

 Present appointments:

  • Consultant in Renal Medicine, Salford Royal NHS Foundation Trust, Northern Care Alliance NHS Foundation Trust: 2006 – present
  • Honorary Lecturer, University of Manchester: 2014 – present

Previous appointments:

  • Specialist Registrar, North-West Deanery: 1999 – 2002
  • Research Registrar, Salford Royal NHS Foundation Trust: 2002 – 2004
  • Specialist Registrar, North-West Deanery: 2004 – 2006

Research interests/expertise:

  • Epidemiological research in the Salford Kidney Study (SKS)
  • Chronic kidney disease
  • Epidemiology of kidney transplantation (in particular recurrent glomerulonephritis and urinary tract infections)


Supervision at higher degrees (co-supervisor of 3 consultant trainees).


Publications (last 5 years):


Chukwu CA, Holmberg C, Storrar J, Middleton R, Sinha S, Kalra PA, Shawki H, Rao A. Clinical and histopathologic predictors of recurrent glomerulonephritis after kidney transplantation. Clin Transplant. 2023 Mar 23:e14970.


Pullerits K, Garland S, Rengarajan S, Guiver M, Chinnadurai R, Middleton RJ, Chukwu CA, Kalra PA. Kidney Transplant-Associated Viral Infection Rates and Outcomes in a Single-Centre Cohort. Viruses. 2022 Oct 29;14(11):2406.

Chukwu CA, Rao A, Kalra PA, Middleton R. Managing recurrent urinary tract infections in kidney transplant recipients using smartphone assisted urinalysis test. J Ren Care. 2022 Jun;48(2):119-127.

Poulikakos D, Chinnadurai R, Anwar S, Ahmed A, Chukwu C, Moore J, Hayes E, Gorton J, Lewis D, Donne R, Lamerton E, Middleton R, O’Riordan E. Increasing Uptake of COVID-19 Vaccination and Reducing Health Inequalities in Patients on Renal Replacement Therapy-Experience from a Single Tertiary Centre. Vaccines (Basel). 2022 Jun 13;10(6):939.

Chukwu CA, Mahmood K, Elmakki S, Gorton J, Kalra PA, Poulikakos D, Middleton R. Evaluating the antibody response to SARS-COV-2 vaccination amongst kidney transplant recipients at a single nephrology centre. PLoS One. 2022 Mar 10;17(3):e0265130.

Middleton RJ, Gorton J, O’Riordan E, Knight S, Kalra PA, Poulikakos D. Impact of Shielding and First Dose of COVID-19 Vaccination in Kidney Transplant Recipients. Nephron. 2022;146(1):64-66.


Alderson HV, Chinnadurai R, Ibrahim ST, Asar O, Ritchie JP, Middleton R, Larsson A, Diggle PJ, Larsson TE, Kalra PA. Longitudinal change in c-terminal fibroblast growth factor 23 and outcomes in patients with advanced chronic kidney disease. BMC Nephrol. 2021 Oct 2;22(1):329.


Lodge MDS, Abeygunaratne T, Alderson H, Ali I, Brown N, Chrysochou C, Donne R, Erekosima I, Evans P, Flanagan E, Gray S, Green D, Hegarty J, Hyde A, Kalra PA, Lamerton E, Lewis D, Middleton R, New D, Nipah R, O’Donoghue D, O’Riordan E, Poulikakos D, Rainone F, Raman M, Ritchie J, Sinha S, Wood G, Tollitt J. Safely reducing haemodialysis frequency during the COVID-19 pandemic. BMC Nephrol. 2020 Dec 7;21(1):532.

Chukwu CA, Middleton R, Kalra PA. Recurrent glomerulonephritis after renal transplantation. Curr Opin Nephrol Hypertens. 2020 Nov;29(6):636-644.


Raman M, Green D, Middleton RJ, Kalra PA. Comparing the impact of older age on outcome in chronic kidney disease of different etiologies: a prospective cohort study. J Nephrol. 2018 Dec;31(6):931-939.

Raman M, Middleton RJ, Kalra PA, Green D. Outcomes in dialysis versus conservative care for older patients: A prospective cohort analysis of stage 5 Chronic Kidney Disease. PLoS One. 2018 Oct 26;13(10):e0206469.

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