This study is designed to accelerate progress towards highly-effective drug therapies for amyotrophic lateral sclerosis (ALS, the commonest form of motor neurone disease, MND). The study will screen candidate drugs in those living with ALS, more quickly identifying those with signals of likely clinical benefit, that may then be prioritised for testing in larger placebo-controlled trials
An innovative drugs trial designed to speed up the time it takes to find medicines that can slow, stop, or reverse the progression of, MND. It will initially test medicines that are already approved as treatments for other diseases. This means there is a reduced risk of adverse effects in trial participants. Repurposing drugs in this way also avoids some of the lengthy approvals processes needed for new drugs and could cut years off the time taken for the medications to become more widely available.
This national study is examining the factors that influence quality of life in patients with neurological conditions, such as multiple sclerosis and motor neurone disease.