Understanding what can trigger or increase the risk of a flare of inflammatory bowel disease

Study summary

The aim of the study is to help understand how factors in the environment, including diet and gut bacteria increase or reduce the risk of a flare in Crohn’s and colitis.

These conditions, known as  inflammatory bowel disease (IBD), affect about 1 in 200 (mostly young) people in the UK. They can cause troublesome and limiting symptoms, typically abdominal pain, bloody diarrhoea, nausea and lethargy. This can have a negative impact on education, employment and relationships. Although the treatments are generally effective they can have nasty side effects and don’t always work well.

Who can take part?

People with established Crohn’s disease, ulcerative colitis and inflammatory bowel disease unclassified (IBDU) who are currently in clinical remission

What will the research involve?

You will be asked to provide stool (poo) and saliva  samples as well as completing a weighed food and drink diary for 4 days.  You will  also be  asked to complete online questionnaires at the start of the study and then every month for two years.

If  you experience a flare whilst on the study, you will be asked to send a stool  sample to the research team, which will help to provide information about this flare.

Where will the research take place?

Gastrointestinal and Inflammatory  Bowel Disease clinics at participating sites, including Salford Royal

Study references

Ethics approved references for this study are listed below

  • Research Ethics committee ref 16/WM/0152

For more information, please contact the study team

Email melanie.taylor@srft.nhs.uk or predicct@ed.ac.uk

Ring 0161 206 0145